Breast cancer diagnosis system using hybrid support vector machine-artificial neural network

Abstract

Breast cancer is the second most common cancer occurring in women. Early detection through mammogram screening can save more women’s lives. However, even senior radiologists may over-diagnose the clinical condition. Machine learning (ML) is the most used technique in the diagnosis of cancer to help reduce human errors. This study is aimed to develop a computer-aided detection (CAD) system using ML for classification purposes. In this work, 80 digital mammograms of normal breasts, 40 of benign and 40 of malignant cases were chosen from the mini MIAS dataset. These images were denoised using median filter after they were segmented to obtain a region of interest (ROI) and enhanced using histogram equalization. This work compared the performance of artificial neural network (ANN), support vector machine (SVM), reduced features of SVM and the hybrid SVM-ANN for classification process using the statistical and gray level co-occurrence matrix (GLCM) features extracted from the enhanced images. It is found that the hybrid SVM-ANN gives the best accuracy of 99.4% and 100% in differentiating normal from abnormal, and benign from malignant cases, respectively. This hybrid SVM-ANN model was deployed in developing the CAD system which showed relatively good accuracy of 98%.